| 摘要 |
Discloses a modified FIX polypeptide comprising the modifications of R338E and T343R in a mature FIX polypeptide having the sequence of SEQ ID NO: 3, wherein the peptide is 95% identical to SEQ ID NOs: 2, 3, 20 and 394, the polypeptide does not contain modifications in F342I/T343R/Y345T and has increased procoagulant activity. |
