PROCESS FOR THE PREPARATION OF (1S, 3AR,6AS)-2-[(2S)-2-({(2S)-2-CYCLOHEXYL-2-[(PYRAZIN-2-YLCARBONYL)AMINO]ACETY}-3,3-DIMETHYIBUTANOYL]-N-[(3S)-1-(CYCLOPROPYLAMINO)-1,2-DIOXO HEXAN-3-YL]-3,3A,4,5,6,6A-HEXAHYDRO-1H-CYCLOPENTA[C]PYRROLE-1-CARBOXAMIDE AND ITS INTERMEDIATES

摘要

The present invention relates to process for the preparation of (1S,3aR,6aS)-2-[(2S)-2-({(2S)-2-cyclohexyl-2-[(pyrazin-2-ylcarbonyl)amino]acetyl}amino)-3,3-dimethylbutanoyl]-N-[(3 S)-1 -(cyclopropylamino)-1,2-dioxohexan-3-yl]-3,3a,4,5,6,6a-hexahydro-1 H-cyclopenta[c] pyrrole-1-carboxamide compound represented by the following structural formula-1. Formula-1 The present invention also provides processes for the preparation of intermediates of compound of formula-1.