| 摘要 |
<p>A protective device for freeze-dried excipient preparation. The device is a cavity opening at two ends, and comprises three parts which are a feed end (1), freeze-dried excipient preparation (2), and a discharge end (3). The freeze-dried excipient preparation is mainly composed of active ingredient and binder. The ratio of the content of the binder in the freeze-dried excipient preparation after being freeze-dried to the volume of the freeze-dried excipient preparation is 0.1mg/ml to 600mg/ml (w/v). The methods for preparing the freeze-dried excipient preparation comprise freeze-drying in situ and freeze-drying following by assembly.</p> |
