| 发明名称 |
ANTIPYRETICS TO ENHANCE TOLERABILITY OF VESICLE-BASED VACCINES |
| 摘要 |
A method for immunising a human subject, wherein the subject receives (i) an immunogenic composition comprising bacterial vesicles and (ii) an antipyretic, and wherein the immunogenic composition and the antipyretic are administered to the subject within 24 hours of each other. Paracetamol significantly reduces fever rates without negatively affecting the immunogenicity either of a meningococcal vesicle vaccine or of concomitantly-administered antigens. |
| 申请公布号 |
US2015147356(A1) |
申请公布日期 |
2015.05.28 |
| 申请号 |
US201214117280 |
申请日期 |
2012.05.11 |
| 申请人 |
Kimura Alan;Dull Peter |
发明人 |
Kimura Alan;Dull Peter |
| 分类号 |
A61K39/095;A61K45/06;A61K35/74 |
主分类号 |
A61K39/095 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for immunising a human subject, wherein the subject receives (i) an immunogenic composition comprising bacterial vesicles and (ii) an antipyretic, and wherein the immunogenic composition and the antipyretic are administered to the subject within 24 hours of each other. |
| 地址 |
Hopkinton MA US |
