Biomatrix Hydrogels and Methods of Use Thereof

摘要

This invention is directed to aragonite and calcite hydrogel biomatrices, optionally seeded with precursor cells and uses thereof in tissue engineering, regeneration and repair, including in inducing or enhancing bone formation, cartilage formation or a combination thereof in a subject, and kits related thereto.

主权项

1. A hydrogel biomatrix comprising a marine organism skeletal derivative biomatrix, wherein said marine organism skeletal derivative is characterized by a specific fluid uptake capacity value of at least 75%, which specific fluid uptake capacity value is determined by establishing a spontaneous fluid uptake value divided by a total fluid uptake value wherein said fluid is water, or said fluid is a protein-containing, salt-containing or carbohydrate containing solution.