发明名称 |
USE OF G-CSF DIMER IN THE TREATMENT OF NEUTROPENIA |
摘要 |
This invention relates to a use of G-CSF dimer in the treatment of neutropenia. In particular, the recombinant human G-CSF of the present invention can enhance the differentiation and development of neutrophils in animal, and thus effectively reduce the severity of the severe neutropenia and shorten the time of severe neutropenia for the post-chemotherapy cancer patients. Serum half-life of G-CSF dimer of this invention is prolonged and the biological activity thereof is increased, providing a better effect in the treatment of neutropenia. |
申请公布号 |
US2015147290(A1) |
申请公布日期 |
2015.05.28 |
申请号 |
US201414526382 |
申请日期 |
2014.10.28 |
申请人 |
Generon (Shanghai) Corporation, LTD. |
发明人 |
YAN Xiaoqiang;Huang Zhihua;Yang Hongzhou;Sun Bill N.;Huang Yuliang |
分类号 |
A61K47/48;A61K38/19 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
1. A method of treating neutropenia in an individual comprising administering to the individual a human granulocyte colony-stimulating factor (G-CSF) dimer. |
地址 |
Shanghai CN |