METHODS OF TREATING CANCER WITH LIPID-BASED PLATINUM COMPOUND FORMULATIONS ADMINISTERED INTRAPERITONEALLY

摘要

PROBLEM TO BE SOLVED: To provide a method comprising administering platinum compounds as part of a lipid-based formulation with low sub-acute toxicity.SOLUTION: The present invention relates to a method of treating cancer in a patient comprising administering to the patient intraperitoneally a cancer treating effective amount of a lipid-based platinum compound formulation. In one embodiment, a method of treating cancer in a patient comprises administering to the patient intraperitoneally a cancer treating effective amount of a lipid-based platinum formulation. In certain embodiments, a platinum compound in the platinum formulation is administered intraperitoneally at a concentration of about 0.8 mg/ml to about 1.2 mg/ml.