SOLID ORAL DOSAGE FORM FOR BREAST SYMPTOMS

摘要

The invention is a solid oral dosage form that is designed to deliver a supraphysiological dose of molecular iodine of 3 to 60 mg per day. The solid oral dosage form is designed to have a low risk of thyroid related adverse clinical events for patients with deficiencies of certain minerals. The solid oral dosage form includes a source of iodine, a reactive agent, and calcium or iron. The solid oral dosage form may include one or more of selenium, vitamin A, vitamin D, zinc, gamma-linolenic acid, vitamin B1, and magnesium. The solid dosage form may further comprise an enteric coating that coats ingredients that are absorbed predominantly from the intestines, such as vitamin A and D, and does not coat the source of iodine and the reactive agent.

主权项

1. A solid oral dosage form, comprising
a source of iodine, a reactive agent, and either calcium or iron, wherein
(i) the source of iodine is unreactive when in the solid oral dosage form,(ii) the total iodine in the solid oral dosage form is 3 to 60 milligrams,(iii) the source of iodine reacts with the reactive agent in simulated gastric fluid, and(iv) the solid oral dosage form, when placed in simulated gastric fluid for a period of up to 2 hours, generates a ratio of molecular iodine to total iodine in the range of 0.8 to 1.0 by weight.