| 摘要 |
<p> A compound represented by the formula (in the formula, R2 and R3 both represent hydrogen atoms or, together with the binding carbon atoms, form a cyclopropyl ring or cyclobutyl ring, R1 represents a group selected from group Q1, and X represents a single bond; or R3 represents a hydrogen atom, and R1 and R2 are the same or different and represent groups selected from group Q1), or a pharmaceutically acceptable salt thereof, the compound and salts exhibiting an exceptional LCAT activating effect and being useful as an active ingredient of an agent for the treatment or prevention of arteriosclerosis, arteriosclerotic heart disease, coronary heart disease (including heart failure, myocardial infarction, angina pectoris, cardiac ischemia, cardiovascular disorders, and angioplasty restenosis), cerebrovascular disease (including stroke and cerebral infarction), peripheral vascular disease (including diabetic vascular complications), dyslipidemia, low HDL cholesterol, or renal disease, and especially being useful as an anti-arteriosclerotic.</p> |
