摘要 |
<p>Provided are: a variant reverse transcriptase, which contains a domain corresponding to a connection domain of a wild-type reverse transcriptase and in which, on hydrophobic surface containing conformationally consecutive hydrophobic amino acid residues in said domain, at least one of the hydrophobic amino acid residues is substituted with a positively-charged amino acid residue; a means for supplying said variant reverse transcriptase; and utilization of the same.</p> |