发明名称 Peptide Inhibitors of Caspase 2 Activation
摘要 The present invention relates to compositions, including membrane permeable complexes, comprising a Caspase 2 activation inhibitory peptide having the amino acid sequence AFDAFC as well as methods of using the same for the treatment of neurodegenerative conditions associated with apoptosis in the central nervous system, such as Alzheimer's Disease, Mild Cognitive Impairment, Parkinson's Disease, amyotrophic lateral sclerosis, Huntington's chorea, and Creutzfeld-Jacob disease.
申请公布号 US2015148302(A1) 申请公布日期 2015.05.28
申请号 US201414201132 申请日期 2014.03.07
申请人 The Trustees of Columbia University in the city of New York 发明人 Troy Carol M.
分类号 C07K7/06;A61K38/08;A61K47/48 主分类号 C07K7/06
代理机构 代理人
主权项 1. A Caspase 2 activation inhibitor composition comprising the amino acid sequence AFDAFC.
地址 New York NY US