MEASUREMENT OF SERUM LIPOPROTEINS

摘要

Although a more accurate estimate of a person's risk of cardiovascular disease can be made on the basis of the number of lipoprotein particles per unit volume in the person's blood, current methods all rely on measuring the mass of lipoprotein cholesterol per unit volume. It has been discovered that a rapid and accurate lipoprotein particle count can be obtained by photometry. A method and apparatus are provided for measuring the number of lipoprotein particles in a sample using photometry.

主权项

1. A method for quantifying a lipid in a sample, the method comprising:
a. separating the sample into at least an LDL fraction, an IDL fraction, and a VLDL fraction; b. obtaining photometric measurements of at least one of the LDL fraction, the IDL fraction, and the VLDL fraction; and c. calculating a particle count for each fraction from which a photometric measurement was obtained, wherein the particle count is an approximately linear function of the photometric measurement.