发明名称 |
ARYLQUINOLINE AND ANALOG COMPOUNDS AND USE THEREOF TO TREAT CANCER |
摘要 |
The subject technology relates to arylquinoline compounds and their use for treating cancer or cancer metastasis. The compounds of the subject technology promote cells to secrete a pro-apoptotic tumor suppressor, i.e., prostate apoptosis response-4 (Par-4), which in turn promote apoptosis in cancer cells or metastatic cells. |
申请公布号 |
WO2015077550(A1) |
申请公布日期 |
2015.05.28 |
申请号 |
WO2014US66796 |
申请日期 |
2014.11.21 |
申请人 |
UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION |
发明人 |
WATT, DAVID S.;LIU, CHUNMING;RANGNEKAR, VIVEK;SVIRIPA, VITALIY M.;BURIKHANOV, RAVSHAN;ZHANG, WEN |
分类号 |
A61K31/47;A61K31/4725;A61P35/00;C07D215/00 |
主分类号 |
A61K31/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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