发明名称 |
PRDM14 and FAM19A4, molecular diagnostic markers for HPV-induced invasive cancers and their high-grade precursor lesions |
摘要 |
<p>The invention relates to method for detecting HPV-induced high- grade precancerous lesions and HPV-induced invasive cancers, said method comprising detection of hypermethylation in the PRDM14 and/or FAM19A4 gene in a cell whereby such hypermethylation indicates the presence of HPV-induced precursor lesions with invasive potential and HPV-induced invasive cancers. The invention further comprises the use of the PRDM14 and/or FAM19A4 gene in such a method and a testkit for the detection of PRDM14 and/or FAM19A4 methylation.</p> |
申请公布号 |
AU2013330509(A1) |
申请公布日期 |
2015.05.28 |
申请号 |
AU20130330509 |
申请日期 |
2013.10.14 |
申请人 |
SELF-SCREEN B.V. |
发明人 |
MEIJER, CHRISTOPHORUS JOANNES LAMBERTUS MARIA;SNIJDERS, PETRUS JOSEPHUS FERDINANDUS;STEENBERGEN, RENSKE DANIELA MARIA |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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