| 发明名称 |
SPECIFIC BIOMARKERS FOR HEPATOCELLULAR CARCINOMA (HCC) |
| 摘要 |
The invention relates to specific marker proteins (biomarkers) for Hepatocellular carcinoma (HCC). The invention relates to a method for the diagnostic study of biological samples of a human for Hepatocellular carcinoma, the sample being studied for one or more proteins as a marker for Hepatocellular carcinoma, a concentration of the proteins which is elevated or decreased in relation to the healthy state indicating the presence of Hepatocellular carcinoma, a diagnostic test kit and a method of screening compounds effective in HCC. |
| 申请公布号 |
US2015147761(A1) |
申请公布日期 |
2015.05.28 |
| 申请号 |
US201314409520 |
申请日期 |
2013.06.20 |
| 申请人 |
Meyer Helmut E.;Sitek Barbara;Megger Dominik A.;Bracht Thilo;Baba Hideo Andreas;Schlaak Joerg Friedrich;Weber Frank |
发明人 |
Meyer Helmut E.;Sitek Barbara;Megger Dominik A.;Bracht Thilo;Baba Hideo Andreas;Schlaak Joerg Friedrich;Weber Frank |
| 分类号 |
G01N33/574;H01J49/04;H01J49/40;G01N30/72;C07K14/47;G01N27/447 |
主分类号 |
G01N33/574 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for identifying biomarkers specific for a particular disease comprising the steps
a) determining if a particular protein is differentially expressed in cause of this particular disease by 2-D gel electrophoresis and b) determining if this particular protein is differentially expressed in cause of this particular disease by liquid chromatography-mass spectrometry (LC-MS). |
| 地址 |
Recklinghausen DE |
