发明名称 |
NEW TREATMENT OF CHRONIC ULCERS |
摘要 |
The present invention provides a pharmaceutical formulation comprising LL-37 or a pharmaceutically-acceptable salt thereof and one or more pharmaceutically-acceptable diluent or carrier system, for use in a method of treatment of a chronic ulcer wound (such as a hard- to-heal venous leg ulcer or a diabetic foot ulcer), which method comprises: (a) topical application of said formulation to said ulcer; followed by (b) application of a dressing, and wherein said application of said formulation provides for a dose of LL-37 at the wound site that is below about 80 μg of LL-37 applied per cm2 of wound area, and/or below about 26.7 μg of LL-37 applied per cm2 of wound area, per day of treatment. |
申请公布号 |
WO2015075441(A1) |
申请公布日期 |
2015.05.28 |
申请号 |
WO2014GB53415 |
申请日期 |
2014.11.19 |
申请人 |
LIPOPEPTIDE AB |
发明人 |
GRONBERG, ALVAR;DIETERICH, CHRISTINE;MAHLAPUU, MARGIT |
分类号 |
A61K38/17;A61K9/70;A61L15/32;A61L15/44;A61L15/60;A61P17/02 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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