Antibodies that interact with interleukin-1 receptor type 1 (IL-1 R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1 R1 are described. Methods of detecting the 5 amount of IL-1 R1 in a sample using antibodies to IL-1 R1 are described.
申请公布号
AU2012202672(B2)
申请公布日期
2015.05.28
申请号
AU20120202672
申请日期
2012.05.08
申请人
AMGEN INC.;E. R. SQUIBB & SONS, L.L.C.
发明人
ELLIOTT, GARY S.;MARTIN, FRANK;VARNUM, BRIAN;VEZINA, CHRIS;WITTE, ALISON;QIAN, XUEMING;HUANG, HAICHUN