发明名称 |
Diketopiperazine salts for drug delivery |
摘要 |
A pharmaceutically-acceptable salt of a heterocyclic compound according to Formula 1:
wherein R 1 or R 2 comprise at least one carboxylate functional group;
E 1 and E 2 are either N or O;
said salt further comprises at least one cation; and
wherein said salt is not a lithium salt of 2,5-diaspartyl-3,6-diketopiperazine or 2,5-diglutamyl-3,6-diketopiperazine and said salt is in a solid form. |
申请公布号 |
EP2322180(B1) |
申请公布日期 |
2015.05.27 |
申请号 |
EP20100075511 |
申请日期 |
2005.08.23 |
申请人 |
MANNKIND CORPORATION |
发明人 |
LEONE-BAY, ANDREA;MOYE-SHERMAN, DESTARDI;WILSON, BRYAN R. |
分类号 |
A61K31/4965;A61K31/357;A61K31/535;C07D241/08 |
主分类号 |
A61K31/4965 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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