| 发明名称 |
ACID CERAMIDASE INHIBITORS AND THEIR USE AS MEDICAMENTS |
| 摘要 |
The present invention concerns, in a first aspect, compounds of Formula I as defined herein, pharmaceutically acceptable salts thereof and pharmaceutical compositions containing such compounds. The present invention also relates to compounds of Formula I for use as acid ceramidase inhibitors, and in the treatment of cancer and other disorders in which modulation of the levels of ceramide is clinically relevant. |
| 申请公布号 |
EP2875006(A1) |
申请公布日期 |
2015.05.27 |
| 申请号 |
EP20130739362 |
申请日期 |
2013.05.27 |
| 申请人 |
FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;UNIVERSITÀ DEGLI STUDI DI PARMA |
发明人 |
PIOMELLI, DANIELE;REALINI, NATALIA;MOR, MARCO;PAGLIUCA, CHIARA;PIZZIRANI, DANIELA;SCARPELLI, RITA;BANDIERA, TIZIANO |
| 分类号 |
C07D239/54;C07D239/545;C07D239/553;C07D239/557 |
主分类号 |
C07D239/54 |
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