发明名称 ENZYMATIC PERACID GENERATION FOR USE IN ORAL CARE PRODUCTS
摘要 Disclosed herein are compositions and methods to treat an oral cavity surface with a peracid-based benefit agent. The peracid benefit agent can be use for oral surface bleaching, whitening, disinfecting, destaining, deodorizing, decreasing or removing biofilm, and combinations thereof. The peracid is enzymatically generated from a carboxylic acid ester substrate using a CE-7 carbohydrate esterase having perhydrolytic activity (perhydrolase) in the presence of a source of peroxygen. A fusion protein comprising the perhydrolase coupled to a peptidic component having affinity for an oral cavity surface, either directly or through an optional linker, may be used to target the perhydrolytic activity to the oral cavity surface.
申请公布号 EP2654695(A4) 申请公布日期 2015.05.27
申请号 EP20110850480 申请日期 2011.12.19
申请人 E. I. DU PONT DE NEMOURS AND COMPANY 发明人 BUTTERICK, LISA, A.;CUNNINGHAM, SCOTT, D.;DICOSIMO, ROBERT;FOSSER, KARI, A.;GRUBER, TANJA, MARIA;HAYNIE, SHARON, L.;PAYNE, MARK, S.;ROUVIERE, PIERRE, E.;WANG, HONG
分类号 A61K8/37;A61K8/35;A61K8/65;A61K8/66;A61Q11/00;C12N9/18 主分类号 A61K8/37
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