Process for the production of beta-amino acids with the use of acylase

摘要

The purpose of the present invention is to provide a process for the selective production of an S-, or R-²-amino acid, which is advantageous in view of cost and will generate a by-product having a low toxicity. The present invention relates to Variovorax sp. which produces an acylase having an asymmetric hydrolysis activity of an N-acetyl ²-amino acid to selectively produce an R-²-amino acid, and Burkholderia sp. which produces both an acylase having an asymmetric hydrolysis activity of an N-acetyl ²-amino acid to selectively produce an S-²-amino acid and an acylase having an asymmetric hydrolysis activity of an N-acetyl ²-amino acid to selectively produce R-²-amino acid, and a process for the selective production of an S-, or R-²-amino acid using the above strains.