发明名称 |
Solid dispersions comprising an amorphous body composed of a heterocyclic anti-tumor compound |
摘要 |
<p>[PROBLEMS] The object is to improve the absorbability of a heterocyclic compound including s-triazine and a pyrimidine derivative in vitro. [MEANS FOR SOLVING PROBLEMS] Disclosed is, for example, an amorphous body of a heterocyclic compound as represented by the general formula (I) [wherein each of R's and others is as defined in the description] including s-triazine and a pyrimidine derivative, or a hydrate, a solvate or a pharmaceutically acceptable salt of the heterocyclic compound. Also disclosed is a process for producing the amorphous body Further disclosed are: a solid dispersion comprising the amorphous body; and a medicinal preparation comprising the solid dispersion.</p> |
申请公布号 |
EP2409975(B1) |
申请公布日期 |
2015.05.27 |
申请号 |
EP20110168461 |
申请日期 |
2008.11.21 |
申请人 |
ZENYAKU KOGYO KABUSHIKIKAISHA |
发明人 |
SUGAMA, TADAAKI;ISHIHARA, NOBUHIRO;TANAKA, YOSHIHARU;TAKAHASHI, MASAYUKI;YAGUCHI, SHINICHI;WATANABE, TETSUO |
分类号 |
C07D403/04;A61K9/16;A61K9/20;C07D413/14 |
主分类号 |
C07D403/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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