| 发明名称 | Methods of treatment using D-serine | ||
| 摘要 | Methods of treatment using D-serine to target brain cells expressing GluN3 subunit-containing triheteromeric NMDARs are disclosed. The methods include inhibiting calcium ion uptake by brain cells, treating epilepsy, and treating seizures by artificially administering D-serine. | ||
| 申请公布号 | US9040581(B1) | 申请公布日期 | 2015.05.26 |
| 申请号 | US201414185421 | 申请日期 | 2014.02.20 |
| 申请人 | The Florida State University Research Foundation, Inc. | 发明人 | Kumar Sanjay |
| 分类号 | A61K31/195;A61K31/198 | 主分类号 | A61K31/195 |
| 代理机构 | GrayRobinson, P.A. | 代理人 | Ramsey Christopher M.;GrayRobinson, P.A. |
| 主权项 | 1. A method of inhibiting calcium ion uptake by brain cells, the method comprising artificially administering D-serine to brain cells expressing GluN3 subunit-containing triheteromeric NMDARs, the amount of D-serine being effective to inhibit calcium ion uptake by the cells. | ||
| 地址 | Tallahassee FL US | ||