发明名称 |
Mediator for test sensor |
摘要 |
A method of forming a 3-phenylimino-3H-phenothiazine or a 3-phenylimino-3H-phenoxazine mediator includes providing a first reactant including phenothiazine or phenoxazine, providing a first solvent, providing a second reactant and providing a second solvent. The first reactant, first solvent, second reactant and second solvent are combined to form a reactants solution. Sodium persulfate is added to the reactants solution to couple the first and second reactants resulting in a reaction solution including the 3-phenylimino-3H-phenothiazine or the 3-phenylimino-3H-phenoxazine mediator. |
申请公布号 |
US9039878(B2) |
申请公布日期 |
2015.05.26 |
申请号 |
US201213717024 |
申请日期 |
2012.12.17 |
申请人 |
BAYER HEALTHCARE LLC |
发明人 |
Marfurt Karen L.;Arndt Henry C. |
分类号 |
G01N27/327;C12Q1/00;C07D265/38;C07D279/18;C07D279/20 |
主分类号 |
G01N27/327 |
代理机构 |
Nixon Peabody LLP |
代理人 |
Nixon Peabody LLP |
主权项 |
1. A test sensor including a base, the base including an enzyme adapted to react with an analyte, and a mediator, the mediator having a background current being less than 200 nA after being exposed to a temperature of 50° C. for a duration of two weeks and further including a neutralizing agent, the neutralizing agent being present in an amount to obtain a pH in a range below 7 to about 5.5 in a mediator solution. |
地址 |
Whippany NJ US |