PIPERIDIN- OG PIPERAZIN-1-CARBOXYLSYREAMIDDERIVATER OG BESLÆGTEDE FORBINDELSER SOM MODULATORER AF FEDTSYREAMIDHYDROLASE (FAAH) TIL BEHANDLINGEN AF ANGST, SMERTE OG ANDRE TILSTANDE

摘要

Certain piperazinyl and piperidinyl urea compounds are useful as FAAH inhibitors. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by fatty acid amide hydrolase (FAAH) activity. Thus, the compounds may be administered to treat, e.g., anxiety, pain, inflammation, sleep disorders, eating disorders, or movement disorders (such as multiple sclerosis).