| 发明名称 | Producing dicarboxylic acids using polyketide synthases | ||
| 摘要 | The present invention provides for a polyketide synthase (PKS) capable of synthesizing a dicarboxylic acid (diacid). Such diacids include diketide-diacids and triketide-diacids. The invention includes recombinant nucleic acid encoding the PKS, and host cells comprising the PKS. The invention also includes methods for producing the diacids. | ||
| 申请公布号 | US9040282(B2) | 申请公布日期 | 2015.05.26 |
| 申请号 | US201314038488 | 申请日期 | 2013.09.26 |
| 申请人 | The Regents of the University of California | 发明人 | Katz Leonard;Fortman Jeffrey L;Keasling Jay D |
| 分类号 | C12N1/20;C12N9/88;C12N9/10 | 主分类号 | C12N1/20 |
| 代理机构 | Kilpatrick Townsend & Stockton LLP | 代理人 | Kilpatrick Townsend & Stockton LLP |
| 主权项 | 1. A recombinant polyketide synthase (PKS) capable of synthesizing a dicarboxylic acid (diacid), said PKS comprising a loading module containing a beta-keto acyl carrier protein synthase Q domain (KSQ) lacking decarboxylase activity, one or more extender modules and a thioesterase (TE) domain. | ||
| 地址 | Oakland CA US | ||