SYSTEMS AND METHODS FOR CARDIAC RHYTHM VARIABILITY ANALYSIS

摘要

Systems and methods are provided for the study of the cardiac rhythm variability. These systems and methods include the recording of the electrocardiogram (EKG), with subsequent calculation of the duration of the beat-to-beat intervals (i.e., R-R intervals), drawing up of the rhythmograms, and additional systems and methods that include determination of, throughout all observation times within particular intervals included in the recording periods, the average values of the informational entropy of the beta-distribution (AE) of the R-R intervals, the differences between the maximum and minimum values of the informational entropy of the beta-distribution (MDE) of the R-R intervals, the root-mean-square deviations of the informational entropy of the beta-distribution (RMSDE) of the R-R intervals, and/or variation factors of the informational entropy of the beta-distribution (VFE) by means of calculation of the informational entropy of the beta-distribution of the R-R intervals.

主权项

1. A computer based system for cardiac rhythm variability analysis of an electrocardiogram, wherein the electrocardiogram includes a plurality of recorded R-R intervals, comprising:
a computer processor unit; and a non-transitory computer readable medium operably associated with the computer processor unit, the non-transitory computer readable medium storing instructions executable by the computer processor unit to perform the steps of: determining an average value of an informational entropy of a beta-distribution of the plurality of R-R intervals; determining a difference between a maximum value and a minimum value of the informational entropy of the beta-distribution of the plurality of R-R intervals; determining a root-mean-square deviation value of the informational entropy of the beta-distribution of the plurality of R-R intervals; and determining a variation factor percentage of the informational entropy of the beta-distribution of the plurality of R-R intervals.