INTEGRATED DEVICE WITH EXTERNAL LIGHT SOURCE FOR PROBING DETECTING AND ANALYZING MOLECULES
摘要
Apparatus and methods for analyzing single molecule and performing nucleic acid sequencing. An integrated device includes multiple pixels with sample wells configured to receive a sample, which, when excited, emits radiation; at least one element for directing the emission radiation in a particular direction; and a light path along which the emission radiation travels from the sample well toward a sensor. The apparatus also includes an instrument that interfaces with the integrated device. Each sensor may detect emission radiation from a sample in a respective sample well. The instrument includes an excitation light source for exciting the sample in each sample well.
申请公布号
CA2930834(A1)
申请公布日期
2015.05.21
申请号
CA20142930834
申请日期
2014.11.17
申请人
QUANTUM-SI INCORPORATED
发明人
ROTHBERG, JONATHAN M.;KABIRI, ALI;SICKLER, JASON W.;GYARFAS, BRETT J.;LACKEY, JEREMY;SCHMID, GERARD;CIPRIANY, BENJAMIN;JEWELL, JACK;WEST, LAWRENCE;FERRIGNO, MICHAEL;GLENN, PAUL E.;BELLOFIORE, ANTHONY