发明名称 |
Immune-tolerance inducer |
摘要 |
The purpose of the present invention is to create an immune-tolerance inducer used in therapy in which donor hematopoietic cells are transplanted into a recipient in order to induce immune tolerance in the recipient with respect to donor cells, tissue, or organs. By using an alpha-galactosylceramide-containing liposome in combination with a costimulatory-pathway-blocking substance, hematopoietic chimerism can be induced in the recipient by the transplantation of donor hematopoietic cells, making it possible to induce immune tolerance in the recipient with respect to donor cells, tissue, or organs. |
申请公布号 |
AU2013339046(A1) |
申请公布日期 |
2015.05.21 |
申请号 |
AU20130339046 |
申请日期 |
2013.11.05 |
申请人 |
REGIMMUNE CORPORATION;TOKYO WOMEN'S MEDICAL UNIVERSITY |
发明人 |
HIRAI, TOSHIHITO;OMOTO, KAZUYA;TANABE, KAZUNARI;KAWAGUCHI, EMI;ISHII, YASUYUKI;MORITA, HARUHIKO |
分类号 |
A61K31/7032;A61K9/127;A61K39/395;A61K45/00;A61P37/06;A61P43/00 |
主分类号 |
A61K31/7032 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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