OCULAR TEAR FILM PEAK DETECTION AND STABILITZATION DETECTION SYSTEMS AND METHODS FOR DETERMINING TEAR FILM LAYER CHARACTERISTICS

摘要

Ocular surface interferometry (OSI) devices, systems, and methods are disclosed for peak detection and/or determining stabilization of an ocular tear film. Embodiments disclosed herein also include various image capturing and processing methods and related systems for providing various information about a patient's ocular tear film (e.g., the lipid and aqueous layers) and a patient's meibomian glands that can be used to analyze tear film layer thickness(es) (TFLT), and related characteristics as it relates to dry eye.

主权项

1. An apparatus for peak detection of a tear film layer thickness(es) (TFLT), comprising:
a control system configured to:
receive a plurality of images containing optical wave interference of specularly reflected light from a region of interest of an ocular tear film captured by an imaging device while illuminated by a multi-wavelength light source;convert at least a portion of each image among the plurality of images representing the optical wave interference of the specularly reflected light from at least a portion of the region of interest of the ocular tear film into at least one color-based value;measure the TFLT of the at least a portion of the region of interest of the ocular tear film in each image among the plurality of images based on a comparison of the at least one color-based value to a tear film layer optical wave interference model;determine a peak TFLT from a measured TFLT of the at least a portion of the region of interest of the ocular tear film among the plurality of images; andgenerate a resulting image comprising the peak TFLT for the at least a portion of the region of interest of the ocular tear film.