发明名称 EMULSIONS OR MICROEMULSIONS FOR USE IN ENDOSCOPIC MUCOSAL RESECTIONING AND/OR ENDOSCOPIC SUBMUCOSAL DISSECTION
摘要 The present invention relates to a pharmaceutical composition in form of emulsion or microemulsion and the use thereof as aid during endoscopic procedures in which it is injected in a target tissue in order to form a cushion. More in details, the invention relates to a method for performing an endoscopic procedure, which comprises injecting said pharmaceutical composition in form of emulsion or microemulsion in a target tissue of a patient, in order to form a cushion, which cushion is then optionally subjected to an endoscopic surgical procedure, such as a resection.
申请公布号 US2015141526(A1) 申请公布日期 2015.05.21
申请号 US201414546925 申请日期 2014.11.18
申请人 COSMO TECHNOLOGIES LTD. 发明人 MORO Luigi;LONGO Luigi Maria;FRIMONTI Enrico;REPICI Alessandro
分类号 A61L31/14;A61L31/06;A61K47/10;A61K47/22;A61K9/00;A61K9/107 主分类号 A61L31/14
代理机构 代理人
主权项 1. A pharmaceutical composition in the form of an emulsion or a microemulsion comprising: (a) an aqueous phase; (b) an oily phase; (c) at least one surfactant; (d) at least one poloxamer; (e) methylene blue or indigo carmine; and (f) at least one physiologically acceptable excipient;wherein said at least one poloxamer is present in an amount below the critical gelation concentration (CGC), and wherein said composition remains in liquid phase up to a temperature of about 40° C. in vitro.
地址 Dublin IE
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