KINASE INHIBITORS

摘要

The disclosed molecules are inhibitors of Bcr-Abl and Src kinases. The molecules are cytotoxic to Gleevec resistant cells. Inhibitors of Bcr-Abl and Src kinases are used in the treatment of Chronic Myelogenous Leukemia among other diseases.

主权项

1. A formulation having kinase inhibitor activity, the formulation comprising:
a first component selected from the group consisting of quinolones, isoquinolines, quinazolines, their derivatives, and mixtures thereof; and a pharmaceutically acceptable delivery vehicle.