| 主权项 |
1. A compound represented by formula (I):wherein
Q is Q1, Q2, or Q3 Z is H or OH; Y is Y′ or Y1 which are divalent groups of formula wherein
A1 and A2 are independently absent or are (C1-C6)alkylene, (C3-C8)cycloalkylene, or (C3-C8)heterocycloalkylene optionally substituted by one or more substituents selected from the group consisting of (C1-C6)alkyl, aryl(C1-C6)alkyl, and heteroaryl(C1-C6)alkyl;B is absent or is (C3-C8)cycloalkylene, (C3-C8)heterocycloalkylene, arylene, or heteroarylene, optionally substituted by one or more groups selected from the group consisting of halogen, nitrile, linear or branched (C1-C6)alkyl, linear or branched (C1-C6)haloalkyl, (C1-C6)alkoxy, aryl, aryl(C1-C6)alkyl, —NR7(R8) and heteroaryl;C and C′ are absent, or are independently —O—, —CO—, —OC(O)—, —C(OO)—, or one of the following groups C1-C14 wherein R7, R7′ and R8 are independently H or linear or branched (C1-C6)alkyl, (C3-C8)cycloalkyl, (C3-C8)cycloalkyl(C1-C6)alkyl, (C3-C8)heterocycloalkyl(C1-C6)alkyl, aryl, or aryl(C1-C6)alkyl, optionally substituted by one or more substituents selected from the group consisting of (C1-C6)alkyl, halo(C1-C6)alkyl, halogen atom, (C1-C6)alkoxy, and halo(C1-C6)alkoxy;D is absent or is (C1-C6)alkylene, arylene, heteroarylene, and (C3-C8)heterocycloalkylene, optionally substituted by one or more (C1-C6)alkyl groups;n, n′, m and p are independently 0 or an integer from 1 to 3;E is absent or is —O— or —OC(O)—; G is arylene optionally substituted by one or more substituents selected from the group consisting of halogen atom, —OH, oxo (═O), —SH, —NO2, —CN, and —NH2; R1 and R2 are independently H or (C1-C6)alkyl or aryl, optionally substituted by one or more halogen atoms; M is —N(R3)—; R3 is H or (C1-C6)alkyl; R4 is a group of formula J1or a pharmaceutically acceptable salt thereof. |
