CYCLIC PEPTIDE

摘要

A cyclic peptide (10) includes two domains (D1,D2), each including three charged sub-domains (14, 16). The first domain (D1 ) includes two anionic sub-domains (14) followed by a cationic sub-domain (16). The second domain (D2) includes two cationic sub-domains (16) followed by an anionic sub-domain (14). The two domains are connected to one another and separated by a tri-glycyl linker (12). The cyclic peptide (10) is able to self-assemble into a network able to mimic an extracelluar matrix, and which promotes cell growth whilst resisting biofilm formation.