NOVEL MONASCUSPURPURONES, PREPARATION PROCESS THEREOF, AND USES OF THE MONASCUSPURPURONES

摘要

The present invention relates to a novel monascuspurpurone compound of formula (I):;;or a pharmaceutically acceptable derivative thereof as described in the specification, the process for preparation of the same, and the composition comprising the same. The uses of a monascuspurpurone compound for promoting adipocyte differentiation, for increasing the activity of PPARγ and/or C/EBPα, for lowering blood glucose, for preventing and/or treating a disease or disorder related to insulin resistance, and for preventing and/or treating metabolic syndrome or its complications are also provided.

主权项

1. A compound of formula (I): or a pharmaceutically acceptable derivative thereof, wherein R1 and R2 are independently selected from the group consisting of alkyl, alkenyl, and carbonyl and R3 is alkyl.