摘要 |
PROBLEM TO BE SOLVED: To provide wound-healing compositions and treatments.SOLUTION: Methods and compositions comprising an anti-osteopontin agent and/or a PDGF receptor-blocker or antagonizing agent, alone or in combination with one or more anti-connexin agents, e.g., one or more anti-connexin polynucleotides, and/or one or more anti-connexin peptides or peptidomimetics, are provided for the promotion and/or improvement of wound healing, and/or tissue repair, and for anti-scarring, anti-inflammatory, anti-fibrosis and anti-adhesion indications. |