METHOD FOR DIAGNOSING ACUTE ALCOHOLIC HEPATITIS

摘要

Various methods for determining whether a subject has alcoholic hepatitis are described. In one aspect, a method for determining whether a subject has alcoholic hepatitis is described. The method includes determining the levels of a trimethylamine in a biological sample obtained from the subject. The level of trimethylamine in the biological sample is compared to the control value, and the subject whose level of trimethylamine exceeds the control value is diagnosed as having alcoholic hepatitis. In another aspect of the present invention a method for assessing a subject as having alcoholic hepatitis (AH) includes determining the level of trimethylamine and the level of pentane in a biological sample obtained from the subject. A TAP score is determined based on the concentration of trimethylamine and the concentration of pentane. The subject is diagnosed as having alcoholic hepatitis if the TAP score exceeds a control value.

主权项

1. A method for assessing a subject as having alcoholic hepatitis (AH) comprising:
receiving an exhaled breath sample from a subject; determining the level of trimethylamine (TMA) and the level of pentane in the exhaled breath sample obtained from the subject using an analytical device; determining a TAP score based on the concentration of trimethylamine and the concentration of pentane in the exhaled breath; and diagnosing the subject as having alcoholic hepatitis based on the TAP score.