发明名称 |
NOVEL COMPOSITIONS AND METHODS FOR TREATING IgE-MEDIATED DISORDERS |
摘要 |
The present invention relates to immunoglobulins that bind IgE and FcγRIIb with high affinity, said compositions being capable of inhibiting cells that express membrane-anchored IgE. Such compositions are useful for treating IgE-mediated disorders, including allergies and asthma. |
申请公布号 |
US2015139985(A1) |
申请公布日期 |
2015.05.21 |
申请号 |
US201414510037 |
申请日期 |
2014.10.08 |
申请人 |
XENCOR, INC. |
发明人 |
DESJARLAIS JOHN;CHU SEUNG Y.;HORTON HOLLY M.;BERNETT MATTHEW J. |
分类号 |
C07K16/42 |
主分类号 |
C07K16/42 |
代理机构 |
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代理人 |
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主权项 |
1. An antibody comprising a heavy chain having SEQ ID NO:42 and a light chain having SEQ ID NO:40. |
地址 |
MONROVIA CA US |