发明名称 |
BIONANOFLUID FOR USE AS A CONTRAST, IMAGING, DISINFECTING AND/OR THERAPEUTIC AGENT |
摘要 |
There is provided a bionanofluid including a carbon-based nanomaterial substantially mono-dispersed in a fluid, wherein the carbon-based nanomaterial is surface modified with a polar group when the fluid is polar or with a non-polar group when the fluid is non-polar, and functionalized with a biological targeting moiety to allow specific association of the carbon-based nanomaterial to a targeted entity. Also provided is a hybrid bionanofluid including the bionanofluid, wherein the carbon-based nanomaterial is further modified with a hybrid nanoparticle which includes an alloy, transition metal, semi-conductor, semi- metal or polymer based nanoparticle with biological targeting moiety. A hydrogel, foam, cream, spray or dried product including the bionanofluid or hybrid bionanofluid is also provided. The bionanofluid or hybrid bionanofluid are useful in multimodal imaging (photo-luminescence, luminescence, photo-acoustic, MRI, ultrasound) and/or cellular targeting. |
申请公布号 |
CA2930441(A1) |
申请公布日期 |
2015.05.21 |
申请号 |
CA20142930441 |
申请日期 |
2014.11.14 |
申请人 |
THE ROYAL INSTITUTE FOR THE ADVANCEMENT OF LEARNING / MC GILL UNIVERSITY |
发明人 |
TRIFIRO, MARK;PALIOURAS, MILTIADIS;ROCHE, PHILIP;DOTAN, IDIT;BEITEL, LENORE;CARNEVALE, MATTHEW;MITMAKER, ELLIOT JONATHAN;ALVARADO, CARLOS |
分类号 |
A61K49/22;A61K9/10;A61K41/00;A61K47/04;A61K49/08;C08J3/075;C08J9/00;C08K3/04;C08L89/06 |
主分类号 |
A61K49/22 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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