| 发明名称 |
EBNA1 INHIBITORS AND THEIR METHOD OF USE |
| 摘要 |
Pharmaceutical compositions of the invention comprise EBNA1 inhibitors useful for the treatment of diseases caused by EBNA1 activity such as cancer, infectious mononucleosis, chronic fatigue syndrome, multiple sclerosis, systemic lupus erythematosus and rheumatoid arthritis. Pharmaceutical compositions of the invention also comprise EBNA1 inhibitors useful for the treatment of diseases caused by latent Epstein-Barr Virus (EBV) infection. Pharmaceutical compositions of the invention also comprise EBNA1 inhibitors useful for the treatment of diseases caused by lytic Epstein-Barr Virus (EBV) infection. |
| 申请公布号 |
CA2930584(A1) |
申请公布日期 |
2015.05.21 |
| 申请号 |
CA20142930584 |
申请日期 |
2014.11.14 |
| 申请人 |
THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY |
发明人 |
MESSICK, TROY E.;SMITH, GARRY R.;REITZ, ALLEN B.;LIEBERMAN, PAUL M.;MCDONNELL, MARK E.;ZHANG, YAN;VELVADAPU, VENKATA |
| 分类号 |
C07D295/155;A61K31/192;A61K31/195;A61K31/381;A61K31/395;A61K31/40;A61K31/404;A61K31/415;A61K31/4184;A61K31/4192;A61K31/426;A61K31/437;A61K31/44;A61K31/4439;A61K31/47;A61K31/4709;A61K31/495;A61K31/4985;A61K31/505;A61P31/22;C07C63/00;C07C229/54;C07D207/04;C07D209/08;C07D213/55;C07D215/12;C07D249/06;C07D401/02;C07D403/06;C07D417/06;C07D471/04;C07D487/04 |
主分类号 |
C07D295/155 |
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