发明名称 COMPOSITIONS AND METHODS FOR THE TREATMENT OF RADIATION EXPOSURE
摘要 The invention provides methods for the treatment of radiation exposure featuring agents that interfere with the expression, production, release, accumulation, or activity of a TNFα, IL6, EGF, IL1-alpha, IL1-beta, G-CSF, MCP-1, MIP-1, SCF, or RANTES receptor; or a TNF-α, IL6, EGF, IL1-alpha, IL1-beta, G-CSF, MCP-1, MIP-1, SCF, or RANTES peptide or fragment thereof.
申请公布号 US2015140009(A1) 申请公布日期 2015.05.21
申请号 US201414463324 申请日期 2014.08.19
申请人 GeneSys Research Institute 发明人 Goukassian David A.
分类号 C12N15/113 主分类号 C12N15/113
代理机构 代理人
主权项 1. A method of ameliorating the effects of radiation exposure on a cell, the method comprising contacting the cell with an agent that selectively reduces the expression or activity of one or more of a p75 TNF-α, p55 TNF-α, IL6, EGF, IL1-beta, G-CSF, MCP-1, MIP-1, SCF, or RANTES receptor in the cell relative to an untreated control cell, thereby ameliorating the effects of radiation exposure on the cell.
地址 Brighton MA US