发明名称 |
Optimized expression cassette for expressing a polypeptide with high yield |
摘要 |
The present invention is based on the finding that the combination of a specific 5'UTR polynucleotide sequence (see SEQ ID NO 1) and the hCD33 secretory leader sequence in an expression cassette for expressing a polypeptide of interest results in a surprisingly better expression level of the polypeptide of interest compared to prior art expression cassettes. Based on this finding, the present invention |
申请公布号 |
AU2013349844(A1) |
申请公布日期 |
2015.05.21 |
申请号 |
AU20130349844 |
申请日期 |
2013.11.18 |
申请人 |
NOVARTIS AG |
发明人 |
DRAGIC, ZORICA;SCHMITZ, RITA;WILMS, BURKHARD |
分类号 |
C12N15/85;C12N5/10 |
主分类号 |
C12N15/85 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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