发明名称 Substituted phthalazin-1 (2H)-one derivatives as selective inhibitors of poly (ADP-ribose) polymerase-1
摘要 The present invention relates to novel compounds of general formula (I), their stereoisomers, regioisomers, tautomeric forms and novel intermediates involved in their synthesis, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates and pharmaceutical compositions containing them. The present invention also relates to a process of preparing novel compounds of general formula (I), their stereoisomers, regioisomers, their tautomeric forms, their pharmaceutically acceptable salts, pharmaceutically acceptable solvates, pharmaceutical compositions containing them, and novel intermediates involved in their synthesis. The compounds of formula (I) are useful as PARP-1 inhibitors for the treatment of, e.g. cancer.
申请公布号 AU2013368842(A1) 申请公布日期 2015.05.21
申请号 AU20130368842 申请日期 2013.12.23
申请人 CADILA HEALTHCARE LIMITED 发明人 SRIVASTAVA, BRIJESH K.;DESAI, RANJIT C.;PATEL, PANKAJ R.
分类号 C07D237/32;A61K31/502;A61P35/00;C07D487/04;C07D491/048;C07D495/04;C07D498/04;C07D513/04 主分类号 C07D237/32
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