发明名称 |
Process for the stereoselective enzymatic hydrolysis of 5-methyl-3-nitromethyl-hexanoic acid ester |
摘要 |
<p>The present invention relates to processes for the preparation of 5-methyl-3-nitromethyl-hexanoic acid ester and its salts. Also disclosed are processes for the preparation of 5-methyl-3-nitromethyl-hexanoic acid salt and a process for the preparation of 3-(aminomethyl)-5- methylhexanoic acid. (S)-5-Methyl-3-nitromethyl-hexanoic acid or (R)-5-methyl-3-nitromethyl-hexanoic acid in enantioenriched form or enantiopure form as well as salts thereof, (S)-5-methyl-3-nitromethyl-hexanoic acid ester or (R)-5-methyl-3-nitromethyl-hexanoic acid ester in enantioenriched form or enantiopure form and a compound, namely Formula (XIII), in racemic form, enantioenriched form or enantiopure form are also disclosed.</p> |
申请公布号 |
AU2009248750(B2) |
申请公布日期 |
2015.05.21 |
申请号 |
AU20090248750 |
申请日期 |
2009.05.19 |
申请人 |
SANDOZ AG |
发明人 |
BERGER, ANDREAS;SALCHENEGGER, JOERG;ZEPECK, FERDINAND;OSL, DORIS;LUSCHNIG, DANIEL;ALBERT, MARTIN;REMLER, PETER;DE SOUZA, DOMINIC;SCHWAB, HELMUT;RIETHORST, WAANDER |
分类号 |
C12P7/40;C07C205/51;C07C229/08;C12P7/62;C12P13/00;C12P41/00 |
主分类号 |
C12P7/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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