METHOD FOR PRODUCING CARBOXYLIC ACID AMIDE

摘要

A carboxamide can be produced in a high yield by a method for producing a carboxamide, for example, represented by formula (4) :
(wherein R 1 and R 3 are as defined below), the method comprising a step of allowing a carboxylic acid ester represented by formula (1):
(wherein R 1 represents an optionally substituented C 1 -C 20 hydrocarbon group or an optionally substituented C 3 -C 20 heterocyclic group, and R 2 represents an optionally substituented C 1 -C 20 hydrocarbon group), an amine represented by formula (2):
€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒ€ƒR 3 -NH 2 €ƒ€ƒ€ƒ€ƒ€ƒ(2)
(wherein R 3 represents a hydrogen atom or an optionally substituented C 1 -C 20 hydrocarbon group),
and a formamide compound represented by formula (3):
(wherein R 3 is as defined above)
to react in the presence of a metal alkoxide.