发明名称 |
BIOLOGICAL METHOD FOR PRODUCING CIS-5-HYDROXY-L-PIPECOLINIC ACID |
摘要 |
The present invention provides a method for producing cis-5-hydroxy-L-pipecolic acid. In the production method of the present invention, a gene recombinant microorganism enabling direct production of cis-5-hydroxy-L-pipecolic acid can be used. The present invention also provides such a gene recombinant microorganism. A preferred embodiment of the present invention is characterized in that a gene recombinant microorganism having DNAs encoding proteins involved in the biosynthesis of L-pipecolic acid and a DNA encoding a protein having the L-pipecolic acid cis-5-hydroxylase activity is cultured in a medium, and cis-5-hydroxy-L-pipecolic acid is collected from the medium. |
申请公布号 |
EP2873730(A1) |
申请公布日期 |
2015.05.20 |
申请号 |
EP20130804143 |
申请日期 |
2013.06.12 |
申请人 |
MICROBIOPHARM JAPAN CO., LTD. |
发明人 |
FUJII, TADASHI;TAMURA, KEISUKE |
分类号 |
C12P17/12;C12N1/21;C12N9/02;C12N15/53 |
主分类号 |
C12P17/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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