发明名称 ANTITUMOR AGENT, MARKER FOR TUMOR DETECTION, AND ORAL VACCINE AGENT
摘要 An object of the present invention is to provide an antitumor agent and/or a marker for tumor detection with low invasiveness, few side effects, and high target specificity. Through the use of a recombinant obligate anaerobic gram-positive bacterium as an active ingredient containing a nucleic acid encoding a secretory fusion protein comprising a signal peptide, a low-molecular-weight single-chain antibody, and a functional peptide, an antitumor agent that enables delivery of a functional peptide to a target cell and/or a marker for tumor detection that enables monitoring of therapeutic effects over time are provided.
申请公布号 EP2873726(A1) 申请公布日期 2015.05.20
申请号 EP20130816104 申请日期 2013.07.12
申请人 TEIKYO HEISEI UNIVERSITY 发明人 TAIRA, YUICHIRO;ISHIDA, ISAO
分类号 C12N1/21;A61K35/74;A61K39/02;A61K48/00;A61P35/00;C07K16/28;C07K19/00;C12N15/09;C12Q1/04 主分类号 C12N1/21
代理机构 代理人
主权项
地址