发明名称 |
ANTITUMOR AGENT, MARKER FOR TUMOR DETECTION, AND ORAL VACCINE AGENT |
摘要 |
An object of the present invention is to provide an antitumor agent and/or a marker for tumor detection with low invasiveness, few side effects, and high target specificity. Through the use of a recombinant obligate anaerobic gram-positive bacterium as an active ingredient containing a nucleic acid encoding a secretory fusion protein comprising a signal peptide, a low-molecular-weight single-chain antibody, and a functional peptide, an antitumor agent that enables delivery of a functional peptide to a target cell and/or a marker for tumor detection that enables monitoring of therapeutic effects over time are provided. |
申请公布号 |
EP2873726(A1) |
申请公布日期 |
2015.05.20 |
申请号 |
EP20130816104 |
申请日期 |
2013.07.12 |
申请人 |
TEIKYO HEISEI UNIVERSITY |
发明人 |
TAIRA, YUICHIRO;ISHIDA, ISAO |
分类号 |
C12N1/21;A61K35/74;A61K39/02;A61K48/00;A61P35/00;C07K16/28;C07K19/00;C12N15/09;C12Q1/04 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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