| 发明名称 | Biodegradable polymeric hydrogel composition | ||
| 摘要 | A biodegradable polymeric hydrogel composition including a component A and component B forming a β-aminoester linkage such that the linkage results in gelation, wherein component A is water soluble polymer containing acrylate functionality and component B is a water soluble amine functionality useful for medical applications such as such as drug delivery, tissue engineering, and biomaterials and method of preparation thereof. | ||
| 申请公布号 | US9034930(B2) | 申请公布日期 | 2015.05.19 |
| 申请号 | US201213608742 | 申请日期 | 2012.09.10 |
| 申请人 | Council of Scientific & Industrial Research | 发明人 | Nair Hemant Ravindran;Kulkarni Mohan Gopalkrishna |
| 分类号 | A61K47/32;A61K47/00;C08G65/332;C08G65/333;C08L71/02;A61K47/34;A61L31/14;A61L15/64;A61K31/785;A61L31/10;A61L27/18;A61L27/52;A61L27/58 | 主分类号 | A61K47/32 |
| 代理机构 | St. Onge Steward Johnston & Reens LLC | 代理人 | St. Onge Steward Johnston & Reens LLC |
| 主权项 | 1. A biodegradable polymeric hydrogel composition comprising a water-soluble poly(hydroxyethyl aspartamide) (PHEAAC) having an acrylate group polymerized with a water soluble poly(succinimide) having an amine group to form a β-aminoester linkage between the acrylate group of the PHEAAC and the amine group of the poly(succinimide); wherein the poly(hydroxyethyl aspartamide) (PHEAAC) has a molecular weight in the range of 5,000 to 22,000 Da and has an acrylate modification of between 5 mole % and 53 mole %; and wherein the amine group is selected from the group consisting of primary and secondary amine. | ||
| 地址 | IN | ||