| 发明名称 | DNA encoding antibody molecules which bind IL-17A and IL-17F | ||
| 摘要 | The invention relates to antibody molecules having specificity for antigenic determinants of both IL-17A and IL-17F, therapeutic uses of the antibody molecules and methods for producing said antibody molecules. | ||
| 申请公布号 | US9034600(B2) | 申请公布日期 | 2015.05.19 |
| 申请号 | US201314074880 | 申请日期 | 2013.11.08 |
| 申请人 | UCB Biopharma SPRL | 发明人 | Adams Ralph;Baker Terence Seward;Lawson Alastair David Griffiths |
| 分类号 | C12N15/09;C07K16/24 | 主分类号 | C12N15/09 |
| 代理机构 | Saul Ewing LLP | 代理人 | Saul Ewing LLP ;Trujillo Doreen Yatko |
| 主权项 | 1. An isolated DNA encoding the heavy chain variable domain and the light chain variable domain of a neutralising antibody which binds human IL-17A and human IL-17F, wherein the heavy chain variable domain comprises the sequence given in SEQ ID NO:9 and the light chain variable domain comprises the sequence given in SEQ ID NO:7, or encoding the heavy chain and the light chain of said antibody, wherein the heavy chain comprises the sequence given in SEQ ID NO:15 and the light chain comprises the sequence given in SEQ ID NO: 11. | ||
| 地址 | BE | ||