发明名称 PARTIALLY LOADED ANTIBODIES AND METHODS OF THEIR CONJUGATION
摘要 <p>A protein containing one or more activatable groups, e.g., an antibody, is subjected to partial or complete reduction of one or more such bonds to form reactive groups; the resulting protein is reacted with a drug which is reactive with some of the reactive groups, such as certain radiometals, chelating agents, and toxins, so as to form a conjugate useful in, e.g., in vitro diagnosis, in vivo imaging, and therapy.</p>
申请公布号 CA2558399(C) 申请公布日期 2015.05.19
申请号 CA20052558399 申请日期 2005.03.02
申请人 SEATTLE GENETICS, INC. 发明人 ALLEY, STEPHEN CHARLES;TORGOV, MICHAEL;SUN, MICHAEL
分类号 C07K16/00;A61K38/05;A61K39/395;A61K47/48;A61K49/00;A61P31/00;A61P35/00;A61P37/02;C07K1/107;C07K1/14;C07K14/52;C07K14/575;C07K14/705;G01N33/53 主分类号 C07K16/00
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